Major League Soccer Betting tips & Predictions

Major League Soccer Predictions - USA

Types of bets

USA Major League Soccer

End

Austin FC

Los Angeles FC

1 3.65

X 3.55

2 2.41

Prediction:

Probability: 50%

18 October - 18:00

Atlanta United Fc

DC United

1 2.12

X 4

2 3.55

Prediction:

Probability: 42%

18 October - 18:00

Charlotte FC

Philadelphia Union

1 2.62

X 3.75

2 2.67

Prediction:

Probability: 48%

18 October - 18:00

FC Cincinnati

CF Montreal

1 1.56

X 4.75

2 5.45

Prediction:

Probability: 42%

18 October - 18:00

Columbus Crew

New York Red Bulls

1 1.68

X 4.46

2 5.7

Prediction:

Probability: 49%

18 October - 18:00

Nashville SC

Inter Miami

1 2.38

X 3.92

2 2.82

Prediction:

Probability: 46%

18 October - 18:00

New England Revolution

Chicago Fire

1 2.9

X 3.9

2 2.37

Prediction:

Probability: 49%

18 October - 18:00

New York City

Seattle Sounders

1 2.17

X 3.76

2 3.18

Prediction:

Probability: 54%

18 October - 18:00

Toronto FC

Orlando City SC

1 3.75

X 4.1

2 2.09

Prediction:

Probability: 50%

18 October - 21:00

Colorado Rapids

Los Angeles FC

1 3.6

X 4

2 2

Prediction:

Probability: 53%

18 October - 21:00

Sporting Kansas City

Houston Dynamo

1 2.57

X 3.79

2 2.57

Prediction:

Probability: 43%

18 October - 21:00

Los Angeles Galaxy

Minnesota United

1 2.69

X 3.73

2 2.55

Prediction:

Probability: 43%

18 October - 21:00

Portland Timbers

San Diego FC

1 2.72

X 3.75

2 2.5

Prediction:

Probability: 43%

18 October - 21:00

San Jose Earthquakes

Austin FC

1 2.1

X 3.95

2 3.75

Prediction:

Probability: 45%

18 October - 21:00

Saint Louis City SC

Real Salt Lake

1 2.39

X 3.95

2 2.7

Prediction:

Probability: 42%

18 October - 21:00

Vancouver Whitecaps

FC Dallas

1 1.58

X 4.75

2 5.6

Prediction:

Probability: 55%

Major League Soccer Statistics (Football)

Match stats

Number of matches played 495

% home win 43.84%

% away win 31.31%

% halftime draws 24.85%

% halftime home wins 37.37%

% halftime away wins 25.86%

% halftime draws 36.77%

Goal stats

Goals 1478

Average goals per match 2.99

Average home goals per match 1.63

Average away goals per match 1.35

Stats betting

% matches over 2.5 goals 56.97%

% matches under 2.5 goals 43.03%

BTTS 59.19%

Cleansheet 40.81%

Discipline stats

Yellow cards 2030

Average yellow cards per match 4.1

Red cards 77

Average red cards per match 0.16

Other stats

Corners 4768

Average corners per match 9.63

Major League Soccer Table - USA

#	Team	P	W	D	L	GD	Pts
1	Philadelphia Union	33	20	6	7	+24	66
2	Vancouver Whitecaps	33	18	9	6	+29	63
3	FC Cincinnati	33	19	5	9	+9	62
4	Inter Miami	33	18	8	7	+23	62
5	San Diego FC	33	18	6	9	+19	60
6	Los Angeles FC	33	17	8	8	+25	59
7	Minnesota United	33	16	10	7	+18	58
8	Charlotte FC	33	18	2	13	+7	56
9	New York City	33	17	5	11	+7	56
10	Nashville SC	33	16	6	11	+16	54
11	Orlando City SC	33	14	11	8	+14	53
12	Chicago Fire	33	15	7	11	+8	52
13	Seattle Sounders	33	14	10	9	+9	52
14	Columbus Crew	33	13	12	8	+2	51
15	Austin FC	33	13	8	12	-7	47
16	Portland Timbers	33	11	11	11	-3	44
17	New York Red Bulls	33	12	7	14	+3	43
18	FC Dallas	33	10	11	12	-4	41
19	Real Salt Lake	33	12	4	17	-11	40
20	Colorado Rapids	33	11	7	15	-12	40
21	San Jose Earthquakes	33	10	8	15	-4	38
22	Houston Dynamo	33	9	9	15	-13	36
23	New England Revolution	33	9	8	16	-7	35
24	Saint Louis City SC	33	8	7	18	-14	31
25	Toronto FC	33	5	14	14	-9	29
26	CF Montreal	33	6	10	17	-23	28
27	Sporting Kansas City	33	7	6	20	-24	27
28	Los Angeles Galaxy	33	6	9	18	-21	27
29	Atlanta United Fc	33	5	12	16	-25	27
30	DC United	33	5	10	18	-36	25
1	Philadelphia Union	33	12	4	1	21	40
2	Charlotte FC	33	12	1	3	15	37
3	Nashville SC	33	11	3	2	22	36
4	Inter Miami	33	11	3	3	18	36
5	Seattle Sounders	33	10	6	1	18	36
6	Los Angeles FC	33	11	2	4	18	35
7	Vancouver Whitecaps	33	10	4	2	23	34
8	New York City	33	11	0	5	8	33
9	New York Red Bulls	33	10	3	4	13	33
10	Columbus Crew	33	8	5	3	7	29
11	Real Salt Lake	33	9	1	7	2	28
12	Orlando City SC	33	8	4	5	10	28
13	Minnesota United	33	8	4	5	9	28
14	Austin FC	33	7	7	3	2	28
15	FC Cincinnati	33	8	3	5	5	27
16	Colorado Rapids	33	8	3	5	4	27
17	Portland Timbers	33	7	6	3	3	27
18	San Diego FC	33	7	5	5	8	26
19	Chicago Fire	33	6	6	5	0	24
20	FC Dallas	33	6	3	8	0	21
21	Los Angeles Galaxy	33	6	2	8	-2	20
22	Atlanta United Fc	33	4	7	5	0	19
23	Houston Dynamo	33	5	3	9	-10	18
24	San Jose Earthquakes	33	4	6	6	4	18
25	Saint Louis City SC	33	4	5	7	-5	17
26	Sporting Kansas City	33	4	4	8	-7	16
27	New England Revolution	33	4	3	9	-5	15
28	Toronto FC	33	2	7	7	-4	13
29	DC United	33	2	7	8	-18	13
30	CF Montreal	33	2	6	9	-19	12
1	FC Cincinnati	33	11	2	4	4	35
2	San Diego FC	33	11	1	4	11	34
3	Minnesota United	33	8	6	2	9	30
4	Vancouver Whitecaps	33	8	5	4	6	29
5	Chicago Fire	33	9	1	6	8	28
6	Philadelphia Union	33	8	2	6	3	26
7	Inter Miami	33	7	5	4	5	26
8	Orlando City SC	33	6	7	3	4	25
9	Los Angeles FC	33	6	6	4	7	24
10	New York City	33	6	5	6	-1	23
11	Columbus Crew	33	5	7	5	-5	22
12	San Jose Earthquakes	33	6	2	9	-8	20
13	New England Revolution	33	5	5	7	-2	20
14	FC Dallas	33	4	8	4	-4	20
15	Charlotte FC	33	6	1	10	-8	19
16	Austin FC	33	6	1	9	-9	19
17	Nashville SC	33	5	3	9	-6	18
18	Houston Dynamo	33	4	6	6	-3	18
19	Portland Timbers	33	4	5	8	-6	17
20	CF Montreal	33	4	4	8	-4	16
21	Seattle Sounders	33	4	4	8	-9	16
22	Toronto FC	33	3	7	7	-5	16
23	Saint Louis City SC	33	4	2	11	-9	14
24	Colorado Rapids	33	3	4	10	-16	13
25	Real Salt Lake	33	3	3	10	-13	12
26	DC United	33	3	3	10	-18	12
27	Sporting Kansas City	33	3	2	12	-17	11
28	New York Red Bulls	33	2	4	10	-10	10
29	Atlanta United Fc	33	1	5	11	-25	8
30	Los Angeles Galaxy	33	0	7	10	-19	7
1	Los Angeles FC	6	5	0	1	11	15
2	Philadelphia Union	6	5	0	1	6	15
3	Vancouver Whitecaps	6	4	2	0	13	14
4	Inter Miami	6	4	1	1	10	13
5	Chicago Fire	6	4	1	1	6	13
6	New York City	6	4	0	2	1	12
7	Charlotte FC	6	4	0	2	1	12
8	FC Dallas	6	3	2	1	4	11
9	Minnesota United	6	3	2	1	4	11
10	Saint Louis City SC	6	3	1	2	2	10
11	FC Cincinnati	6	3	1	2	1	10
12	Real Salt Lake	6	3	0	3	-3	9
13	Austin FC	6	3	0	3	-3	9
14	Los Angeles Galaxy	6	2	2	2	2	8
15	CF Montreal	6	2	2	2	0	8
16	San Diego FC	6	2	2	2	0	8
17	Seattle Sounders	6	2	2	2	-1	8
18	Nashville SC	6	2	1	3	3	7
19	Houston Dynamo	6	2	1	3	-3	7
20	Portland Timbers	6	1	3	2	-1	6
21	Columbus Crew	6	1	3	2	-2	6
22	Orlando City SC	6	1	3	2	-4	6
23	San Jose Earthquakes	6	2	0	4	-7	6
24	Toronto FC	6	0	5	1	-2	5
25	DC United	6	1	2	3	-7	5
26	New York Red Bulls	6	1	1	4	-2	4
27	New England Revolution	6	1	1	4	-4	4
28	Colorado Rapids	6	1	1	4	-7	4
29	Atlanta United Fc	6	1	1	4	-7	4
30	Sporting Kansas City	6	1	0	5	-8	3

Playoffs

Qualification Playoffs

Major League Soccer fixtures

12 Oct 19:00

Austin FC

Los Angeles FC

1 0

How are our MLS predictions made?

MLS Prediction 2025-26

At Wincomparator, we've been predicting the MLS since 2008. Now, in 2025, we're bringing you our intelligent predictions, the result of years of research. Our special algorithm enables us to make reliable Major League Soccer predictions.

Our predictions are based on thousands of pieces of data
AI helps us to process the data
The odds on the MLS are taken into account in the calculation
Our experts validate all MLS predictions generated by our tool

We currently have the ability to calculate the most likely outcome of MLS match in October 2025.

Winner prediction: who do we expect to win the MLS Cup?

Best scorer Lionel Messi - MLS

The MLS is shaping up to be particularly tight this year! Indeed, a number of clubs are in with a shout of winning the title in the USA's top league.

Inter Miami, LAFC, Vancouver, Cincinnati, Columbus and new boys San Diego will all believe that this could be their year.

However, our experts have their sights set on two teams in particular: Inter Miami and Seattle.

Miami entered the season as the betting favourites and they have been able to hold on to that title for now. With Lionel Messi and Luis Suarez expectedly putting up huge numbers, the Herons can appear near impossible to stop at times. While manager Javier Mascherano will load manage his superstars throughout the year in an attempt to keep them healthy, expect all the big names to be ready to go by the time the playoffs rolls around.

In the Western Conference, we can't look past the excellent value on offer with Seattle. The Sounders made it to the quarter-finals in 2023 and the semi-finals in 2024 and were able to strengthen their already deep roster in the offseason. They are a team built for knockout football and we expect them to once again be in the mix come the later stages of the MLS Cup Playoffs.

Our prediction: Inter Miami or Seattle Sounders MLS Cup champions!

Who will win the MLS? The odds of the favourite for the title

Inter Miami - 6.00
Vancouver - 7.00
Philadelphia Union - 8.00
San Diego FC - 8.00
LAFC - 8.00
Cincinnati - 11.00
Minnesota Utd - 13.00
Columbus Crew - 21.00
Nashville SC - 21.00
Charlotte - 21.00
NYCFC - 21.00
Seattle Sounders - 26.00
Chicago Fire - 26.00

These odds, taken from the Bet365 website (correct as of 11/10/2025), show that the title will be hotly contested and that winning the MLS is anything but easy. Would you like to bet on the future winner or find out the odds on all the teams? Go to Bet365.com!

Note also that at certain times of the season, you'll have the opportunity to bet on the long term, with bets on which teams will finish atop the Eastern or Western Conference, which team will make it to the MLS Cup final, which player will win the MVP award, or the competition's top goalscorer.

Bet on the MLS

The impact of MLS statistics on your predictions

One thing we've noticed in all our Major League Soccer predictions is that statistics should not be overlooked, and that they play a fundamental role in the success of a bet. In fact, by taking them into account along with other information (such as teams, players, fixtures, etc.), you'll have a much better idea of which bets to favor and which to avoid.

For example, based on the current 2025 MLS season's figures, an Inter Miami or Orlando City match are much more likely to validate the "Over 2.5 goals" prediction (76% and 75%, respectively, the two highest totals in the league). On the contrary, you might want to avoid placing the same type of bet on a Toronto or Austin FC match, which have the two lowest rates at 32% and 37%.

Keep in mind that the main figures and all the statistics should be analysed before each bet on the MLS, and that we offer you our stats table a bit higher up on this page, so don't hesitate to make use of it!

MLS odds: how to use them to bet with bookmakers?

If there's one other thing to remember, it's that the odds offered by betting sites are also crucial to a good betting strategy. It's important to understand that they reflect the probabilities of an outcome, and our algorithm obviously takes them into account in its calculations.

If you're planning to bet on a MLS match, ask yourself this question: are the odds I want to play a true reflection of the match at hand? In other words: are the potential winnings worth the stake? Or am I taking too big of a risk?

For example, say you see Philadelphia in trouble when they take on Columbus, but the bookmakers are offering odds of 1.75 for the Union to win. Using the formula (1/quote) x 100, you can calculate the probability of success for Philadelphia as estimated by the bookmakers, in this case 57.1%.
If you're sticking to your guns and don't see the Union winning, then avoid a bet. It would be a shame to risk €10, for example, to win "only" €7.50. In fact, you may want to consider backing the other side, if you can make a solid case for why they are undervalued.
Reversing the situation now, you can see Cincinnati taking all 3 points from Inter Miami.
The betting sites are offering odds of 2.50 for this bet, which gives a probability of 40% according to the bookmakers.
Here, the odds look really good. Why? The books underestimate Cincinnati in your opinion, and the possible winnings are high in relation to the risk taken!

As you can see, the odds offered by online bookmakers for the MLS are clearly not to be overlooked and should always be taken into account. This is true not only for Major League Soccer, but also for any other football predictions!

Guidelines for reliable Premier League predictions

MLS Betting advice tips

All the MLS predictions on our site are based on over 100 parameters. A real asset if you want to put all the odds in your favour to win as many bets as possible.

If you'd like to carry out an analysis yourself, here are three key tips to apply to your bets on the MLS, especially for punters who are just starting out.

1. Observe the form of key MLS players

Firstly, and probably most importantly, it is necessary to analyse the form of the key players who are preparing to play in the match that you wish to bet on. In the United States more than elsewhere, in addition to almost all sports, we speak of a "franchise player", i.e. the most important player on a team. There can sometimes be several of them, and it is then necessary to identify them.

Their latest performances and their current form will be decisive for your predictions. For example, last year, Denis Bouanga finished as the top scorer in MLS, and helped LAFC finish in third-place in the Western Conference!

2. Beware of low-stakes matches in the USA

It is very important to be aware of what is really at stake in the match you are about to bet on. For example, if a club has already qualified for the playoffs at the end of the season, but is no longer in contention for top spot, it could afford to rest some of its key players in order to be fresh for the second half of the season. The same goes for a club that can no longer qualify for the play-offs and has nothing left to play for at the end of the season, and could probably play the last few games without being 100% focused.

Before betting on the US football championship, you need to take a good look at the official standings and see what is really at stake for a team this season. For example, there is no relegation, so there is no real pressure on the teams at the bottom of the table.

3. Take the time to compare MLS odds between bookmakers

Finally, and this will have a direct impact on your net winnings, we strongly advise you to compare the MLS odds offered by the different bookmakers before placing a bet. It often happens that there is a big difference between two bookmakers for the same type of bet. For example, a big match like Los Angeles FC vs Seattle Sounders might see Unibet offering the home side a win at 1.80, while Vbet will only offer it at 1.70.

At first glance, this may not seem to have much of an impact, but these differences start to add up over the long term. We therefore advise you to sign up with as many bookmakers as possible to guarantee yourself the best odds on the market. What's more, you'll be able to take advantage of the fantastic welcome bonuses offered by the various sports betting sites!

Our opinion on the difficulty of MLS betting

In our experience, while the level of play can sometimes be inconsistent due to not having elite talent such as in Europe's top five leagues, the MLS is not too difficult of a competition to predict. It's a league that can have quite a bit of parity in the sense that there usually isn't a handful of dominant teams year in and year out because of the salary cap system that is in place.

This can make things unpredictable in the first few weeks of the season, but you should be able to quickly hone in on which are the top-performing squads. At Wincomparator, we put you in the best possible position with our expert predictions, PL stats and the best odds to bet on.

Bet on the MLS